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Capecitabine Oral tablet
What is this medicine?
CAPECITABINE (ka pe SITE a been) is a chemotherapy drug. It slows the growth of cancer cells. This medicine is used to treat breast cancer, and also colon or rectal cancer.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
bleeding or blood disorders
dihydropyrimidine dehydrogenase (DPD) deficiency
infection (especially a virus infection such as chickenpox, cold sores, or herpes)
an unusual or allergic reaction to capecitabine, 5-fluorouracil, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
How should I use this medicine?
Take this medicine by mouth with a glass of water, within 30 minutes of the end of a meal. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.
Your doctor may want you to take a combination of 150 mg and 500 mg tablets for each dose. It is very important that you know how to correctly take your dose. Taking the wrong tablets could result in an overdose (too much medication) or underdose (too little medication).
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, do not take the missed dose at all. Do not take double or extra doses. Instead, continue with your next scheduled dose and check with your doctor.
What may interact with this medicine?
antacids with aluminum and/or magnesium
medicines to increase blood counts like filgrastim, pegfilgrastim, sargramostim
Talk to your doctor or health care professional before taking any of these medicines:
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor for checks on your progress. This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
In some cases, you may be given additional medicines to help with side effects. Follow all directions for their use.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medicine.
Avoid taking products that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your doctor. These medicines may hide a fever.
Do not become pregnant while taking this medicine. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.
Men are advised not to father a child while taking this medicine.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
low blood counts - this medicine may decrease the number of white blood cells, red blood cells and platelets. You may be at increased risk for infections and bleeding.
signs of infection - fever or chills, cough, sore throat, pain or difficulty passing urine
signs of decreased platelets or bleeding - bruising, pinpoint red spots on the skin, black, tarry stools, blood in the urine
signs of decreased red blood cells - unusually weak or tired, fainting spells, lightheadedness
changes in vision
diarrhea of more than 4 bowel movements in one day or any diarrhea at night
nausea and vomiting
pain, swelling, redness at site where injected
pain, tingling, numbness in the hands or feet
redness, swelling, or sores on hands or feet
yellow color of skin or eyes
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
dry or itchy skin
loss of appetite
weak or tired
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.
Broward Health Receives Grant to Help Women Navigate Breast Cancer Treatment
Find out more details about the Breast Cancer Navigator Program »
Broward Health provided 29,380 mammograms last year, nearly 3,000 of them for women who had no insurance and could not afford to pay. While a mammogram may be essential in detecting abnormalities, a diagnosis is meaningless without follow-up. That follow-up – particularly for poor women – can be daunting.
A grant of nearly $150,000 from the Florida Division of the American Cancer Society will help Broward Health set up a new Breast Cancer Patient Navigator Program to ensure that more women living in poverty will get the medical care they need after an abnormal mammogram or a diagnosis of breast cancer. The goal is to ensure half of the participants are African-American, Caribbean or Hispanic.
A “navigator” case manager will provide one-on-one assistance to women of any age in navigating the complexities of not only scheduling, testing and treatment, but with things like childcare, transportation, translation services and understanding medical terminology as well.
The navigator case manager will oversee the woman’s care throughout treatment at the Comprehensive Cancer Centers at Broward Health facilities (Broward Health Medical Center and Broward Health North). If the woman doesn’t show up for an appointment, stops treatment, or becomes unreachable after two weeks, the case manager will go to her home to check on her and find out why she hasn’t kept her appointments. The case manager will then work with her to get her back on track. When cancer goes into remission, the case manager will continue to monitor her health and quickly set up doctor appointments and further treatment if needed.
The navigator program is dedicated to dismantling barriers faced by medically underserved women with breast cancer, increasing access to healthcare services and ultimately improving quality of life.
Breast Cancer Patient Navigator Program Participants
September 2006 – July 2008
The American Cancer Society awarded Broward Health the Breast Cancer Patient Navigator Program Grant in September 2006 to navigate medically underserved women of all ages (living below 200% of the Federal Poverty Level who receive an abnormal mammogram), from diagnostic mammogram to breast cancer survivorship. The two (2) year grant award provided for one (1) Registered Nurse Breast Cancer Patient Navigator to remove the barriers to care by providing one-on-one case management once breast cancer is diagnosed.
The program allows for:
- Earlier identification/intervention
- Greater outreach to our community
- A broader range of services
- Decreased treatment variability
- Increased effectiveness of care
- 282 female and 2 male patients, ages 15 thru 85
- 57 dependent children
- Treatment and diagnostic sites – 1-49 miles from patients' home
- Transportation – 60% of the patients were brought to the health care site by friend or family; 34% by private car; 6% used taxi service or public transportation provided by Broward Health
Race/Ethnicity (Claritas 2007)
37% - Black Non Hispanic
51% - Black Non Hispanic
23% - Hispanic
18% – Hispanic
19% - White Non Hispanic
25% - White Non Hispanic
9% - Haitian
3% - Asian
7% - Other
3% - Other
2% - Asian
1% - Portuguese
- 284 - patients referred from Broward Health sites and the Broward County Health Department's Breast & Cervical Cancer Initiative
- 109 - patients that did not meet guidelines (i.e. had insurance, were enrolled in another program, received care at another facility, refused services)
- 63 - patients disenrolled from the program (i.e. eligibility changed, moved, changed providers, chose homeopathic treatment and/or refused treatment, treatment complete and patients are following up with primary care physician for a yearly mammogram)
- 37 - patients in the program with no diagnosis of breast cancer that are being followed.
- 75 - patients with diagnosis of breast cancer – majority of the cases is invasive ductal carcinoma. (61 ductal, 5 intra ductal, 4 multi focal, 3 lobular, 1 mucinous & 2 multi centric)
1 - stage 0
7 - stage I
31 - stage II
18 - stage III
6 - stage IV
12 - in staging process
- Broward Health hospitals and Community Health Service sites, i.e., Broward Health Medical Center, Broward Health North, Broward Health Imperial Point, and Broward Health Coral Springs.
- Broward Health Website
- Florida Breast Cancer Resource Network
- Broward County Health Department through its Breast & Cervical Cancer Initiative (BCCI)
- Other community organizations, i.e., Living Water clinics, Light of the World, churches, etc.
- Private physician offices, friends, and family
Benefits of Program
Access & Compliance
Patients adhered to their scheduled appointments. In the event of a scheduling conflict, the Breast Cancer Patient Navigator was contacted for resolution.
Transportation and certification process has been expedited because of intervention by Breast Cancer Patient Navigator.
97% of the patients adhered to the treatment plan (3% sought alternative treatment or chose treatment elsewhere).
Care & Treatment
Recommended diagnostic procedures:
- Spot magnification / compression
- Stereo tactic biopsy
- Ultrasound biopsy
- CT Scans, Mir's & PET Scans
- Echocardiograms, Lab work, X-rays and ultrasounds
Recommended treatment procedures:
- Hormonal treatment
97% of the patients adhered to scheduled diagnostic procedures
Current status of patient treatment
29 – in treatment (chemo/radiation)
30 – in post treatment
6 – refused treatment
6 – in work-up
1 – out of service area
3 – out of country
Knowledge and Education
Educational components made available to all the patients:
- Initial education packet
- American Cancer Society Breast Cancer Guidelines
- National Cancer Institute Breast Cancer Booklet
- Chemotherapy and You
- Triple Touch
- Knowledge & Education
- Demand Mailings – specific topics of interest
- Support groups and education classes
- Look Good, Feel Better
- Gilda's Club
- Reach to Recovery
- Community Church Support Group