Broward Health North
Stroke Center

Stroke Center

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Aspirin, Dipyridamole Oral capsule, extended-release

What is this medicine?

ASPIRIN; DIPYRIDAMOLE (AS pir in; dye peer ID a mole) is used to decrease the risk of stroke in patients who have had a stroke or transient ischemic attack. A transient ischemic attack is also known as a TIA or mini-stroke.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • asthma

  • bleeding or clotting problems

  • drink more than 3 alcoholic beverages a day

  • kidney or liver disease

  • nasal polyps

  • stomach ulcers, or other stomach problems

  • vitamin K deficiency

  • an unusual or allergic reaction to aspirin, dipyridamole, salicylates, NSAIDs, tartrazine dye, other medicines, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the label. The capsules must be swallowed whole. Do not crush or chew. You can take this medicine with or without food. Take your doses at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • medicines that treat or prevent blood clots like warfarin or heparin

  • methotrexate

This medicine may also interact with the following medications:

  • acetazolamide

  • adenosine

  • antiinflammatory drugs, NSAIDs like ibuprofen

  • aspirin-containing medicines or other salicylates

  • diuretics

  • medicines for Alzheimer's disease or myasthenia gravis

  • medicines for diabetes that are taken by mouth

  • medicines for high blood pressure like ACE inhibitors or beta-blockers

  • medicines for seizures like phenytoin or valproic acid

  • probenecid

  • sulfinpyrazone

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Do not take other aspirin products unless directed by your doctor or health care professional. Many non-prescription medicines contain aspirin. To prevent accidental overdose, read labels carefully and do not take more than one product that contains aspirin.

If you have diabetes, this medicine may affect your blood sugar levels. Check with your doctor or health care professional before you change your diet or the dose of your diabetes medicine.

Aspirin can irritate your stomach. Drinking alcohol and smoking cigarettes can make this irritation worse and may cause ulcers or bleeding problems. Ask your doctor or health care professional for help to stop smoking or drinking. Do not lie down for 30 minutes after taking this medicine to prevent irritation to your throat.

If you are receiving cancer chemotherapy or medicine for your immune system, do not take this medicine without checking with your doctor or health care professional. Aspirin may hide the signs of an infection like fever or pain and increase your risk of bleeding.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • fast, irregular heartbeat

  • pain on swallowing

  • redness, blistering, peeling or loosening of the skin, including inside the mouth or nose

  • ringing in the ears

  • seizure

  • signs and symptoms of bleeding such as bloody or black, tarry stools; red or dark-brown urine; spitting up blood or brown material that looks like coffee grounds; red spots on the skin; unusual bruising or bleeding from the eye, gums, or nose

  • signs and symptoms of a blood clot such as breathing problems; changes in vision; chest pain; severe, sudden headache; pain, swelling, warmth in the leg; trouble speaking; sudden numbness or weakness of the face, arm or leg

  • unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • diarrhea

  • flushing, reddening of the skin

  • headache

  • nausea

  • reduced amount of urine passed

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from excessive heat and moisture. Throw away any unused medicine after the expiration date.


Broward Health North's Stroke Center is recognized as a certified Primary Stroke Center by the Joint Commission on Accreditation of Healthcare Organizations and a Comprehensive Stroke Center by the Agency for Healthcare Administration.

The Joint Commission is the nation's predominant standards-setting and accrediting body in health care. This designation offers the public a way to identify which hospitals offer the best possible outcomes for stroke patients.

At Broward Health North, assessment and treatment begin in the Emergency Department by a specially trained team called the Brain Attack Team (BAT). The BAT is available 24/7 and consists of Emergency Medical Services (EMS and paramedics), emergency medicine physicians, neurologists, neurosurgeons, interventional radiologists, radiologists and nursing staff. Ten nurses at Broward Health North have gone above and beyond to obtain the prestigious Certified Neurological Registered Nurse designation. They are fully prepared to help you and your loved one through this delicate time. Our designated Stroke Unit is equipped with state-of-the-art technology to ensure your loved one receives the best possible care.

If you require rehabilitation after your stroke, Broward Health North’s Inpatient and Outpatient Rehabilitation Unit is here to keep you on a path to recovery. Our rehabilitation unit is accredited by the Commission on Accreditation of Rehabilitation Facilities (CARF) and is the first hospital in Florida to attain Joint Commission Certification for Stroke Rehabilitation.

What is a stroke?

Stroke is a cerebro-vascular disease that affects the arteries leading to and within the brain. Every 45 seconds, someone in America has a stroke. Every three minutes, someone dies of one. It is the third leading cause of death and a leading cause of severe, long-term disability.

Stroke Warning Signs

  • Sudden numbness or weakness of the face, arm or leg, especially on one side of the body
  • Sudden confusion, trouble speaking, swallowing or understanding
  • Sudden trouble seeing in one or both eyes
  • Sudden trouble walking, dizziness, loss of balance or coordination
  • Sudden, severe headache with no known cause
  • If you experience these symptoms, dial 911!

Risk Factors

Some risk factors cannot be changed or controlled like age, family history and gender. However, reducing the following risk factors can prevent a stroke.

  • High blood pressure
  • Cigarette smoking
  • Diabetes
  • High cholesterol
  • Physical inactivity and obesity
  • Heart disease
  • Transient Ischemic Attacks (TIAs) or mini strokes
  • Excessive alcohol and some illegal drugs

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