Clinical Trials


Broward Health's clinical trials program focuses on finding better ways to treat illnesses through a voluntary program between patients and their doctors. A clinical trial is a research study in which individuals receive investigational treatments under the supervision of a physician and other research professionals.

Clinical Trials

Broward Health's clinical trials program focuses on finding better ways to treat illnesses through a voluntary program between patients and their doctors. A clinical trial is a research study in which individuals receive investigational treatments under the supervision of a physician and other research professionals.

What Are Clinical Trials?

Broward Health has a variety of Active Adult and Pediatric Clinical Trials available on a continual basis, which may include medical research in clinical drug trials for the treatment of HIV/AIDS, heart disease, memory disorders, traumatic brain injury, cancer, and other diseases.

Clinical trials are studies in which people volunteer to take part in tests of new drugs or procedures. Doctors use clinical trials to develop new treatments for serious diseases, such as cancer. You may learn more about clinical trials by visiting ClinicalTrials.gov

Current Studies at Broward Health

Clinical trials are studies in which people volunteer to take part in tests of new drugs or procedures. Doctors use clinical trials to develop new treatments for serious diseases, such as cancer. You may learn more about clinical trials by visiting ClinicalTrials.gov

PEDIATRIC HEMATOLOGY ONCOLOGY RESEARCH TRIALS 

  • Leukemia
    • AALL05B1: A Children's Oncology Group Protocol for Collecting and Banking Relapsed Acute Lymphoblastic Leukemia Research Specimens
    • AALL08B1: The Classification of Acute Lymphoblastic Leukemia
    • AALL0932: Treatment of Patients with Newly Diagnosed Standard Risk B-Precursor Acute Lymphoblastic Leukemia (ALL)
    • AALL1131: A Phase III Randomized Trial for Newly Diagnosed High Risk B-Lymphoblastic Leukemia (B-ALL) Testing Clofarabine (IND #73789, NSC #606869) in the Very High Risk Stratum
    • AAML1031: A Phase III Randomized Trial for Patients with de novo AML using Bortezomib (IND #58443, NSC #681239) and Sorafenib (BAY 43-9006, IND #69896, NSC #724772) for Patients with High Allelic Ratio FLT3/ITD
  • Brain & Spine
    • ACNS02B3: A Children's Oncology Group Protocol for Collecting and Banking Pediatric Brain Tumor Research Specimens
    • ACNS0331: A Study Evaluating Limited Target Volume Boost Irradiation and Reduced Dose Craniospinal Radiotherapy 18.00 Gy and Chemotherapy In Children with Newly Diagnosed Standard Risk Medulloblastoma: A Phase III Double Randomized Trial
    • ACNS0831: Phase III Randomized Trial of Post-Radiation chemotherapy in Patients with Newly Diagnosed Ependymoma Ages 1 to 21 Years
  • Ewing Sarcoma
    • AEWS07B1: A Children's Oncology Group Protocol for Collecting and Banking Ewing Sarcoma Specimens
    • AWES07P1: A Phase III Randomized Trial of Adding Vincristine-Topotecan-Cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-metastatic Ewing Sarcoma
  • Germ Cell:
    • AGCT0132: A Phase III Study of Reduced Therapy in the Treatment of Children with Low and Intermediate Risk Extracranial Germ Cell Tumor
  • Liver
    • AHEP0731: Treatment of Children with All Stages of Hepatoblastoma
  • Neuroblastoma
    • ANBL0032: Phase III Randomized Study of Chimeric Antibody 14.18 (Ch14.18) in High Risk Neuroblastoma Following Myeloablative Therapy and Autologous Stem Cell Rescue
    • ANBL00B1: Neuroblastoma Biology Studies
    • ANBL00P3: A Phase III randomized trial of Intravenous Gammaglobulin Therapy for Patients with Neuroblastoma Associated Opsoclonus-Myoclonus-Ataxia Syndrome Treated with Chemotherapy and Prednisone
  • Osteosarcoma/Bone
    • AOST06B1: A Children's Oncology Group Protocol for Collecting and Banking Osteosarcoma Specimens
  • Renal/Kidney
    • AREN03B2: Renal Tumors Classification, Biology, and Banking Study
    • AREN0532: Treatment for Very Low and Standard Risk Favorable Histology Wilms Tumor
    • AREN0533: Treatment of Newly Diagnosed Higher Risk Favorable Histology Wilms Tumors: A Groupwise Phase III Study
  • Rhabdomyosarcoma (Soft Tissue Sarcoma)
    • 9902: A COG Soft Tissue Sarcoma Diagnosis, Biology and Banking Protocol
  • Other
    • ABTR01B1: A Children's Oncology Group Protocol for Collecting and Banking Pediatric Research Specimens Including Rare Pediatric Tumors
    • ACCL0933: A Randomized Open-Label Trial of Caspofungin versus Fluconazole to Prevent Invasive Fungal Infections in Children undergoing Chemotherapy for Acute Myeloid Leukemia (AML)
    • ALTE05N1: Umbrella Long-Term Follow-Up Protocol
    • ACCRN07: Protocol for the Enrollment on the Official COG Registry, the Childhood Cancer Research Network (CCRN)
    • APEC14B1: The Project Every Child Protocol: A Registry, Eligibility Screening, Biology, and Outcome Study

ADULT RESEARCH TRIALS

  • Breast
    • Fujirebio FDI-69: A Prospective Longitudinal Study of CA 15-3 as an Aid in Monitoring Recurrence or Progressive Disease in Patients with Breast Cancer
  • Cardiovascular
    • REDUCE-IT: AMR-01-01-0019: A Multi-Center, Prospective, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Effect of AMAR101 on Cardiovascular Health and Mortality in Hypertriglyceridemic Patient with Cardiovascular Disease or at High Risk for Cardiovascular Disease: REDUCE-IT (Reduction of Cardiovascular Events with EPA - Intervention Trial)
    • B14181038: Phase III Multicenter, Double Blind, Randomized, Placebo Controlled, Parallel Group Evaluation of the Efficacy, Safety and Tolerability of PF-04950615, in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects
    • B1481022: Phase III Multicenter, Double Blind, Randomized, Placebo Controlled, Parallel Group Evaluation of the Efficacy, Safety and Tolerability of PF-04950615, in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects
  • Head & Neck
    • BHMC-001: A Prospectively Acquired Database of Head and Neck Cancer Patients Receiving Radiation Therapy Using Modern Techniques With a Quality of Life Assessment Tool Within the Broward Health Medical System at 21st Century Radiation Oncology Offices
  • Lung
    • AMGEN 20070782: A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Long Term Safety and Efficacy of Darbepoetin Alfa Administered at 500 ug Once Every 3 Weeks in Anemic Subjects with Advanced Stage Non-Small Cell Lung Cancer Receiving Multi-Cycle Chemotherapy 
  • Other
    • Angel Catheter Study: IDE: G120266 QD-230: The Angel® Catheter Clinical Trial: Prevention of Pulmonary Embolism in High Risk Subjects
  • Pancreatic
    • Fujirebio FDI-68: A Prospective Longitudinal Study of CA 19-9 as an Aid in Monitoring Recurrence or Progressive Disease in Patients with Pancreatic Cancer 

Closed Trials

Closed studies are no longer recruiting participants because they already have enough participants, have ended the trial, or have stopped the trials for other reasons. However, those who participated in trials that have since closed may continue to be followed by researchers for additional information. The following are some trials that have closed.

PEDIATRIC HEMATOLOGY ONCOLOGY RESEARCH TRIALS

  • Leukemia
    • AALL0232: High Risk B-precursor Acute Lymphoblastic Leukemia (ALL)
    • AALL0331: Standard Risk B-precursor Acute Lymphoblastic Leukemia
    • AALL0433: Intensive Treatment for Intermediate-Risk Relapse of Childhood B-Precursor Acute Lymphoblastic Leukemia (ALL): A Randomized Trial of Vincristine Strategies
    • AALL0434: Intensified Methotrexate, Nelarabine (Compound 506U78;IND #52611) and Augmented BFM Therapy for Children and Young Adults with Newly Diagnosed T-cell Acute Lymphoblastic Leukemia (ALL)
    • AAML0431: The Treatment of Down Syndrome Children with Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Under the Age of 4 Years
    • AAML0531: A Phase III Randomized Trial of Gemtuzumab Ozogamicin (Mylotarg®) Combined with Conventional Chemotherapy for De Novo Acute Myeloid Leukemia (AML) in Children, Adolescents, and Young Adults
    • 9904: ALinC 17 Treatment for Patients with Low Risk Acute Lymphoblastic Leukemia - A Phase III Study
  • Lymphoma
    • AHOD0031: A Phase III Study of Dose-Intensive, Response-Based Chemotherapy and Radiation Therapy for Children and Adolescents with Newly Diagnosed Intermediate Risk Hodgkin Disease
  • Rhabdomyosarcoma (Soft Tissue Sarcoma)
    • ARST0331: AVincristine, Dactinomycin, and Lower Doses of Cyclophosphamide With or Without Radiation Therapy for Patients with Newly Diagnosed Low-Risk Embryonal/Botryoid/Spindle Cell Rhabdomyosarcoma

ADULT RESEARCH TRIALS

  • Cardiovascular
    • LSS of 4-SITE: Longitudinal Surveillance Study of the 4-SITE Lead/Header System
    • Siello IDE #G110221 (Pre-Market and Post-Approval Registry)
    • STOP-AF Post-Approval Study: Sustained Treatment of Paroxysmal Atrial Fibrillation Post-Approval Study
    • RESPOND-CRT Study: Clinical Trial of the SonRtip Lead and Automatic AV-VV Optimization Algorithm in the PARADYM RF SonR CRT-D

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